The donor sperm is used to fertilise the eggs through ICSI intra-cytoplasmic sperm injection) procedure
For who?- couples with co-existing male factor ( severe low sperm counts or azoospermia) and female factor infertility where the woman cannot or fails to conceive through donor IUI cycles.
This is an advanced technique of IVF where the immature eggs are collected and matured outside in an IVF lab and subjected to IVF/ICSI procedure.
For who? – women with severe PCOS /PCOD at risk of OHSS, as a part of fertility preservation, and even in normal patients to reduce the side effects of high doses of hormones used in a normal ovarian hyper stimulation cycle.
Commonly known as “Test Tube Baby”, IVF is an advanced technique of artificial reproductive procedures. IVF means fertilisation and culture of an ovum (egg) outside the body and consequently transfer of the fertilised ovum (embryo) into the uterus of the women. IVF is probably the most widely practised assisted conception procedure In the world. The procedure usually does not need admission at any step & is conducted on outpatient basis.
The procedure is indicated for irreparably damaged or blocked fallopian tubes and when other modes of treatments has failed in conditions such as:
IUI is one of the simple and basic artificial reproductive techniques used in the treatment of subfertility where the semen of the male partner is collected by masturbation and processed in the laboratory. The seminal plasma is discarded and the best quality sperms are harvested and kept in special culture media. The prepared sample of sperms is then deposited into the uterine cavity with the aid of a thin catheter.
IUI in a Natural cycle – This is a type of procedure where no ovulation induction drugs are used for follicular (egg) development but instead IUI is done in a natural cycle where the woman develops a dominant follicle (egg) spontaneously by herself.
For who? –women with regular ovulatory cycles but with low semen counts, poor sperm motility and or morphology or sexual dysfunction.
What does egg donation means?
Donor egg program includes oocyte retrieval from healthy young oocyte donors after controlled ovarian hyper stimulation followed by IVF/ ICSI
(with male partner‘s sperm) and embryo transfer in recipient’s uterus.
Why cryopreservation?
- Semen with very limited number of spermatozoa or abnormal semen parameters.
- Cancer patients to preserve their fertility prior to gonadotoxic chemotherapy or radiation.
- Patients undergoing certain types of pelvic or testicular surgeries.
- Persons in occupation where significant risk of gonadotoxicity prevails.
- Men undergoing surgical sterilization like vasectomy.
- Allow donor semen samples to be quarantined while performing appropriate screening to prevent transmission of infectious pathogens during donor insemination.
- In combination with ART technique.
- Patient who suffer from degenerative illness like DM, multiple sclerosis, spinal cord, disease, etc.
Ovarian tissue cryopreservation for transplantation
With the newer aggressive treatment regimens, the number of cancer survivors are constantly growing and hence fertility preservation is of high priority. Previously only ovarian stimulation with oocytes or embryo cryopreservation was the only possible option for women to conceive after recovery from a sterilizing cancer treatment. But ovarian stimulation may be incompatible with an urgent cancer treatment cryopreservation.
Transplantation of ovarian tissue helps to overcome such short comings. This technique does not require pre-treatment. It can be performed any day independently of where the patient is in the menstrual cycle. Ovarian tissue banking is a promising clinical technique because it avoids ovarian stimulation and provides opportunity for preserving gonadal function in pre-pubertal as well as adult patient.
Oocyte and embryo cryopreservation
Oocyte cryopreservation or vitrification is a rapidly advancing breakthrough technology in ART where women’s eggs (oocytes) are extracted, frozen and stored. Later when pregnancy is desired, the eggs can be thawed, fertilized and transferred to the uterus.
Fertility and fecundity decreases with age. So women who would like to preserve their future ability to have children, either because they do not have a partner or for other personal or medical reasons. It is done as a part of ART treatment for couples who do not consider embryo freezing an option. It is also performed in those diagnosed with cancer and have not yet begun chemotherapy or radiotherapy.
The egg retrieval process for oocytes cryopreservation is same as that for IVF. The women undergo several weeks of hormonal injection for stimulation. Once the eggs are of adequate size, final maturation induction is performed and eggs are subsequently removed from the body under ultrasound guidance and are frozen using cryoprotectants which replace most of the water within the cells and inhibit formation of ice crystals. The percentage of transfer of cycles is lower in frozen cycles when compared with fresh cycle.
This is a basic step in the treatment of subfertility where medication is given to the female partner between day 2- day 5 for the development of one or more follicles (eggs) from the ovaries. The response to the medicine i.e the growth of the follicles is monitored with the help of serial vaginal scans .once the appropriate size is reached with adequate endometrial thickness uterus lining), HCG or agonist trigger Injection is given for maturation and release of the egg from the ovary And The couple is advised to have intercourse during the most fertile period of the cycle (i.e Timed intercourse) or planned for IUI. After an Hcg trigger, ovulation usually occurs 36–42 hours later and IUI is most commonly performed 32–36 h after hCG administration.
IUI – D (donor) – is an ART (artificial reproductive technique) procedure where in the sperm of an anonymous donor is used for IUI .
For who? –male partner with no sperm count (azoospermia) or very poor sperm parameters which is not treatable or does not respond to medication or surgery.
Frozen Donor sperm samples are obtained only from recognised sperm banks across India. Cultural and physical characteristics of the couple are matched with those of the sperm donor before the procedure and the ICMR guidelines are followed strictly.
Surrogacy is the form of reproductive technology where women offer to carry baby on behalf of someone else or couple and then return the baby to concerned person after the birth. Surrogacy is a complex procedure that has numerous steps which ensures the both parties make best choices including broad directing, psychiatric evaluation and free legal advice. CFC surrogacy program will support you throughout the journey.
In surrogacy, embryo is created utilizing an egg and sperm produced by the parents or donor and is transferred to surrogates uterus.The surrogate has no hereditary connection to the child. Her eggs can’t Surrogates egg cannot be utilized to conceive the child.
Laparoscopy is the minimally invasive diagnostic procedure that includes insertion of narrowtelescope camera system to view the abdominal and reproductive organs such as uterus, fallopian tubes, and ovaries. The fertility expert makes little hole approximately 0.5 to 1 cm in the abdomen, through which fiber optic tube fitted with camera and light is inserted. Suspicious developments can be biopsied and repairs can be made during laparoscopy.
Our fertility expert proposes laparoscopic surgery to help in diagnosing a cause for infertility. Usually Laparoscopy is performed only after other fertility testing has been completed. If patient is experiencing any pelvic pain such as endometriosis, our fertility expert proposes laparoscopic surgery to find the source of pain and remove the defects such as scar tissues, fibroid tumours and other abnormalities.